WebJun 16, 2024 · From the observation, the Theophylline is more soluble in sodium salicylate hydrotrope than other three hydrotropes. Since it is a water soluble molecular structure … WebThe solubility of theophylline – oxalic acid co-crystal and theophylline – glutaric acid co-crystal was determined in 4:1 chlroform – methanol and in pure chloroform respectively. At equilibrium with the solid theophylline – oxalic acid co-crystal, the theophylline concentration is only 60 % of the corresponding value for the
Extended Hildebrand solubility approach: solubility of theophylline …
WebTheophylline is a cyclic phosphodiesterase inhibitor. It antagonizes Adenosine A Receptors and weakly inhibits alkaline phosphodiesterases and 5′-nucleotidase. ... Soluble in water (8.3 g/l) at 20° C, 0.1 M NaOH, 0.1 M HCl, ethanol (moderately), DMSO, alkali hydroxides, ammonia, dilute hyrochloric acid, nitric acid, ... WebC s is the solubility of theophylline and k is the pH of the theophylline solution. The results are shown in Table 4.From the table,it is seen that, the solubility of theophylline increases … dallas vs philly spread
Mechanistic Insight of Polymer Effects on the Kinetic of Solution ...
WebFeb 27, 2024 · Theophylline is a methylxanthine alkaloid that is a competitive inhibitor of phosphodiesterase (PDE; Ki = 100 μM). It is also a non-selective antagonist of adenosine A receptors (Ki = 14 μM for A1 and A2). Theophylline induces relaxation of feline bronchiole smooth muscle precontracted with acetylcholine (EC40 = 117 μM; EC80 = 208 μM). WebCaffeine, theobromine, and theophylline are all more fat soluble than they are water soluble. 5 mo. ago. Thank you! Does the extra methyl group on caffeine (as opposed to theophylline, theobromine and paraxanthine) not make a difference? Patrick26. The presence or absence of that methyl group does affect the solubilities, but they are still ... WebSolubility: Theophylline is lightly soluble in water; soluble in hot water; sparingly soluble in alcohol, chloroform, and ether. It is freely soluble in alkali hydroxide solutions and in ammonia Sweetman (2002). Ionization Constant: Value: Salt: Conditions: Reference: Comments: pKa: 8.77: monohydrate: 25° O'Neil et al (2001) bird-and-flower painting