Smart aiegens promise effective theranostics

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August undefined, 2024

WebOct 7, 2024 · This unique sensing mechanism has been effective for the detection of a wide range of chemical analytes in living cells, tissues, and animals, although bioprobes with additional functionalities are increasingly required in the quest to unravel and understand the complex biological systems.

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WebMay 1, 2024 · Excellent activatable AIE probes have been reported for detecting toxic substances, imaging intracellular active molecules/biomolecules, as well as monitoring … WebAs shown here, AIEgen-based theranostic systems have been extensively investigated and demonstrated to be promising candidates in improving the treatment efficacy. Highly … cynthia weibel erie pa

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WebThese smart AIE probes rely on selective chemical reactions to achieve specific detection and imaging of analytes of interest (e.g., signaling molecules, biothiols, and enzymes), … WebAggregation-induced emission luminogens (AIEgens) that display strong emission in aggregated states, low background, high signal-to-noise ratio and sensitivity, and high resistance to photobleaching, may circumvent this problem. On the other hand, the overuse of anti-bacterial antibiotics diminishes their effect. WebMar 21, 2024 · The applications of aggregation-induced emission luminogens (AIEgens), a particular category of fluorophores, in the field of photo-driven theranostics have been … cynthia weiss antonucci

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Aggregation‐enhanced theranostics: AIE sparkles in …

WebJul 20, 2024 · Phototheranostic agents have thrived as promising tools for cancer theranostics because of the integration of sensitive in situ fluorescence imaging and … WebApr 13, 2024 · With the development of personalized medical demands for precise diagnosis, rational management and effective cancer treatment, supramolecular theranostic systems have received widespread attention due to their reversibly switchable structures, sensitive response to biological stimuli and integration ability for multiple capabilities in a … bimby i remember so many peopleWebAggregation-induced emission (AIE) is an inventive fluorescent technique and has the potential to address this issue. 4,33–51 AIE illustrates a unique photophysical phenomenon where molecules are non-emissive in the discrete state because of active intramolecular motions, but emit energetically when aggregated due to the restriction of … bimby leiria horario

"WebThis research has therefore presented a smart multifunctional material holding great promise in both basic research and clinical practice. Cancer as a leading cause of death in recent decades has been paying close attention owing to … " - Smart aiegens promise effective theranostics

Smart aiegens promise effective theranostics

Aggregation‐enhanced theranostics: AIE sparkles in …

WebSep 9, 2024 · Many AIEgens have been successfully designed, synthesized, and further applied for molecular imaging and image-guided theranostics in neurological diseases … WebDec 15, 2024 · Light-mediated nano-theranostics (LMNT), a type of phototheranostic system, is a promising precision medicine technology. Further, 2,1,3-Benzothiadiazole …

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WebOrganometallic AIEgens (OMAs) possess the merits of both AIEgens (affording “turn-on” type probes in vitro and in vivo) and metal ions (enhancing electron transfer and … WebTo facilitate image-guided theranostics, researchers usually apply a desired amount of photosensitizers to achieve effective photothermal responses. However, these probes could easily suffer from low photostability and aggregated-caused quenching effect …

WebSep 27, 2024 · The benefit is twofold for Skilled Nursing Facilities (SNFs): coordinate care and prepare for safe discharge to the community for short-stay patients and guide care … WebThis review highlights the tremendous aggregation‐enhanced superiorities of AIE luminogens (AIEgens) in disease theranostics mainly involving diagnostic imaging (fluorescence and room temperature phosphorescence), therapeutic intervention (photodynamic therapy), and feasibility in construction of multi‐modality theranostic …

WebApr 4, 2024 · As an antibiotic-free therapy, phototherapy is a promising approach to treat microbial infections due to its spatiotemporal selectivity, non-invasiveness, minimal side … WebSep 8, 2016 · Smart design of simple molecules born with multifunctions should represent one of the future directions in theranostics. Fluorogens with aggregation-induced …

WebNov 19, 2024 · In this work, an enzyme‐mediated aggregation‐induced emission fluorogen (AIEgen) intracellular polymerization strategy that can simultaneously promote the accumulation and retention of the AIEgen in the tumor for prolonged imaging and enhanced tumor growth inhibition is described. An AIEgen‐peptide conjugate (D2P1) and… View on …

WebDec 15, 2024 · Transition metal complex-based AIEgens (TM-AIEgens) combine the advantages of organic AIEgens and transition metal centers to improve photophysical … cynthia weil beautifulWebOct 6, 2024 · NIR-II agents with a PDT property as well as other functions are recently emerging as a powerful tool for boosting the phototheranostic outcome. In this minireview, we summarize the recent advances of photodynamic NIR-II aggregation-induced emission luminogens (AIEgens) for biomedical applications. cynthia weinstein pennington njWebSmart design of simple molecules born with multifunctions should represent one of the future directions in theranostics. Fluorogens with aggregation-induced emission … bimby limitedWebOct 6, 2024 · In this minireview, we summarize the recent advances of photodynamic NIR-II aggregation-induced emission luminogens (AIEgens) for biomedical applications. The molecular design strategies for tuning the electronic bandgaps and photophysical energy transformation processes are discussed. cynthia weinstein montroseWebDec 3, 2024 · The induction of mitochondrial dysfunction can be an effective pathway of chemotherapy, photodynamic therapy, and combination therapy against cancer. This review focuses on recent progress in the field of AIE luminogens (AIEgens) for cancer theranostics based on mitochondrial targeting and dysfunction. bimby leiriaWebFeb 16, 2024 · As innate probes, aggregation-induced emission (AIE) luminogens (AIEgens) exhibit negligible luminescence in the free state but enhanced luminescence in the aggregated or restricted states. Moreover, AIEgen-based nanoparticles (AIE dots) offer efficient luminescence, good biocompatibility and water solubility, and superior … bimby lightWebTheranostics 2024 TLDR It is believed that AIEgens would be promising multifunctional theranostic platforms in clinical fields and facilitate significant advancements in this … bimby i remember so many gif