WebApr 8, 2024 · LncRNA SLC26A4-AS1 suppresses the MRN complex-mediated DNA repair signaling and thyroid cancer metastasis by destabilizing DDX5. ... These four lncRNAs (NR2F1-AS1, Lnc-STAT1-2, NEAT1, and Lnc ... WebApr 7, 2024 · Taken together, we demonstrate that SLC26A4-AS1 promotes NPTX1 transcriptional activity by recruiting NFKB1 and thus exerting antiangiogenic effects on …
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WebLncRNA SLC26A4-AS1 markedly inhibited migration, invasion, and metastasis capability of cancer cells in vitro and in vivo. Intriguingly, SLC26A4-AS1 could simultaneously interact … WebWO2024035950A1 PCT/CN2024/114540 CN2024114540W WO2024035950A1 WO 2024035950 A1 WO2024035950 A1 WO 2024035950A1 CN 2024114540 W CN2024114540 W CN 2024114540W WO 2024035950 A1 WO202 the place coventry
LncRNA SLC26A4-AS1 suppresses the MRN complex …
WebApr 7, 2024 · We determined that SLC26A4-AS1 was downregulated in human glioma tissues and cells. Furthermore, overexpression of SLC26A4-AS1 or NPTX1 restrained the aggressiveness of glioma cells and their pro-angiogenic ability. SLC26A4-AS1 was also found to upregulate NPTX1 by recruiting NFKB1 into the NPTX1 promoter. WebSep 25, 2024 · Notably, SLC26A4‐AS1 elevated E‐cadherin expression while it reduced that of ERK and Vimentin. In addition, the overexpression of SLC26A4‐AS1 inactivated the MAPK pathway by promoting TP53 and decreased cell migration, proliferation, and invasion. In addition to all these effects, the overexpression of SLC26A4‐AS1 promoted apoptosis of ... WebTotal lysates from each cell line were resolved by 4–12% SDS-PAGE and immunoblotted with anti-ALCAM antibodies. Arrow indicates the fully glycosylated ALCAM isoform. Beta-actin was used as a loading control. Techniques Used: Expressing, SDS Page human ptc cell line tpc 1 ( ATCC ) ATCC is a verified supplier ATCC manufactures this product About News the place command