Hif-1α抗体

WebSummary. HIF1 alpha antibody recognizes HIF1 alpha (HIF1a) protein, which is a subunit of the heterodimeric transcription factor hypoxia-inducible factor-1 (HIF-1). HIF-1 is a master regulator of homeostatic adaption to hypoxia (low oxygen supply) in various physiological and pathological conditions including normal development and cancer. WebHIF-1 alpha靶点介绍 蛋白功能. HIF-1 alpha是HIF-1蛋白亚基,由HIF1A基因编码。 HIF-1 alpha是细胞在缺氧条件下生存能力的重要转录调节因子。 HIF-1 alpha在血管形成中起重要作用,其失调与癌症和缺血性疾病病理学有关。 蛋白特性. HIF-1 alpha仅在含氧量低于5%的环 …

DMOG;二甲基乙二酰氨基乙酸_HIF_抑制剂&拮抗剂 ...

Web14 de out. de 2016 · 低酸素症(Hypoxia)に関して,近年注目されているHIF-1α(Hypoxia Inducible Factor-1α)に対する抗体です。腫瘍における低酸素症は,腫瘍悪性度,放射 … WebThe HIF1 complex consists of two subunits, HIF-1α and HIF-1β, which are basic helix-loop-helix proteins of the PAS (Per, ARNT, Sim) family. ... HIF-1α抗体(小鼠单抗) AF1837. 50μl. HIF-1 beta Rabbit Monoclonal Antibody. AF6567. 50μl. CREBBP Rabbit Polyclonal Antibody. AG2135. 50μl. howell nj townhomes for sale https://completemagix.com

HIF-1 alpha Antibody - BSA Free - Novus Biologicals

WebProduct Description. Hypoxia-inducible factor- 1α (HIF- 1α) is a transcription factor that accumulates under low- oxygen conditions. 1, 2 Following hypoxic stimulus and … Web11 de abr. de 2024 · 该团队通过分析多种肿瘤细胞高频缺失的染色体位点,鉴定出了一个具有潜在抑癌活性的lncRNA基因,并将其命名为 HITT(HIF-1α inhibitor at translation level)。前期研究发现HITT可对低氧,DNA损伤等应激因素作出应答,HITT低表达的肿瘤细胞表现为应激压力下的生存优势。 Web)hif-1α同泛素结合,需要e1、e2、e3酶相互传递,最终为靶蛋白加上泛素(泛素化)。 还可以在泛素上面加泛素(因为泛素蛋白自己身上也有泛素化位点),这样可以加上一条长长的泛素链,然后将靶蛋白引向蛋白酶体,蛋白酶体将其“粉碎”水解。 howellnj weather 18218

乙酸钠对氧糖剥夺皮质神经元损伤的作用及HIF-1α表达 ...

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Hif-1α抗体

A deep learning and docking simulation-based virtual screening …

WebImmunogen: peptide corresponding to a sequence at the N-terminus of human HIF-1-alpha. HIF-1 alpha (Hypoxia-inducible factor 1 alpha,HIF1A) is a transcription factor that mediates cellular and systemic homeostatic responses to reduced availability in mammals, including angiogenesis, erythropoiesis and glycolysis. This gene was mapped to 14q21 ... WebSummary. HIF1 alpha antibody recognizes HIF1 alpha (HIF1a) protein, which is a subunit of the heterodimeric transcription factor hypoxia …

Hif-1α抗体

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Web23 de jul. de 2024 · HIF-1α Antibody (28b) is an IgG 1 κ mouse monoclonal HIF-1 alpha antibody (also designated HIF1A antibody or HIF-1 alpha antibody) suitable for the … WebHIF-1α Antibody (28b) is an IgG 1 κ mouse monoclonal HIF-1 alpha antibody (also designated HIF1A antibody or HIF-1 alpha antibody) suitable for the detection of the HIF …

Web31 de mai. de 2024 · 相关文献显示,hif-α在正常环境下不易被检测到,仅少量可进入胞核并结合hif-1β进而产生hif-1复合物而发挥重要作用。 临床研究报道,HIF-1α可通过激活诸多类型基因表达进而作用于糖酵解、葡萄糖摄取等过程。 WebHIF-1α抗体(小鼠单抗) AG2258. 50μl. IL-1β Mouse Monoclonal Antibody. AG2111. 50μl. Phospho-Histone H1.B (Thr146) Rabbit Polyclonal Antibody. AF1837. 50μl. HIF-1 beta Rabbit Monoclonal Antibody.

Web缺氧诱导因子-1α(hypoxia-inducible factor 1α, HIF-1α)属于氧依赖的转录激活因子,在缺氧条件下HIF-1α的转录水平升高,参与肿瘤的生长及侵袭过程[4]。肺腺癌的靶向治疗目前已取得突破性进展,但仍有部分患者不能采用靶向治疗,对于这部分患者我们需要探索新的方法。 WebUse a concentration of 5 µg/ml. Detects a band of approximately 120 kDa (predicted molecular weight: 92 kDa). We recommend blocking for 1 hour with 5% milk in TBST and reducing to 2% milk in TBST for the primary …

Web360 linhas · HIF-1 alpha (clone H1alpha67) was used at 1:500 dilution for WB assays in lysates from human glioblastoma cell lines U87MG and T98G which were left untransfected or transfected with empty vector (Control shRNA) or with Parkin shRNA (Parkin shRNA) … PC12 whole cell lysate is provided as a Western blot positive control. The … Nuclear HIF-1 engages p300/CBP for binding to hypoxic response elements … L929 cells are grown under standard tissue culture conditions until semi-confluent … There are currently no images for Raw 264.7 Lysate (NBP3-11860). Every … Publications using NB200-103 Applications Species; Reis-Barbosa PH, Marinho TS, … Publications using NB300-605 Applications Species; Janani G, Zhang L, Badylak S … CoCl2 inhibits prolyl-hydroxylases (PHD enzymes), the oxygen sensors, through … PHD2/HIF Prolyl Hydroxylase 2 antibody used for WB at 1 : 500 dilution on 30 …

Web21 de jun. de 2024 · HIF-1αと低酸素応答の仕組みについて. 今回は、2024年ノーベル医学・生理学賞をご受賞された「細胞が酸素濃度を感知し応答する仕組みの発見」について、その内容を解説していきたいと思います。. 1. HIF-1αとは. 黒アザラシ. まずは、今回の最も主 … hide a bed sofa ikeaWeb抗HIF1A ウサギ宿主抗体 Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution; Synonyms: 抗ARNT相互作用タンパク質抗体 ウサギ宿主抗体,抗HIF-1α抗体 ウサギ宿主抗体,抗HIF1α抗体 ウサギ宿主抗体,抗PASタンパク質メンバー1抗体 ウサギ宿主抗体,抗低酸素誘導因子1α抗体 ... howell nj weather njWebNational Center for Biotechnology Information howell nj weather mapWebhif-1αは、通常の酸素状態の間は、プロリン残基402と506でヒドロキシル化され、すぐにユビキチン化され、プロテアソームにより分解されます。 しかしながら、低酸素状態では、プロリンのヒドロキシル化が減少するため、HIF-1α分子の分解は防止されます。 howell nj weather radarWebMinimal reactivity occurs with the non-hydroxylated form of the protein. This antibody is specific for HIF-1a hydroxylated at P564. Minimal cross-reactivity occurs with non … hide a bed sofas queenWeb5 de jan. de 2024 · HIF1a Antibody (H1alpha 67) is a mouse monoclonal IgG 2b κ, cited in 183 publications, provided at 200 µg/ml. raised against amino acids 432-528 of HIF-1α of human origin. Anti-HIF1a Antibody (H1alpha 67) is recommended for detection of HIF-1α of mouse, rat and human origin by WB, IP, IF and IHC (P); also reactive with additional … hideabedthat isnt a couchWebNuclear HIF-1 engages p300/CBP for binding to hypoxic response elements (HREs). This process induces transcription and regulation of genes including EPO, VEGF, iNOS2, … hide a bed sofa air mattress