WebUse Screening cytokeratin cocktail; epithelial marker Special Instructions Clearly indicate clinical reason for testing provide the following information: differential diagnosis, site of specimen, and clinical information. Test Includes Option I: Slides and controls are returned for client interpretation WebApr 11, 2024 · We discuss a case of a 64-year-old male patient who presented with a history of RCC and a purpuric nodule on his lateral thigh. Histopathological examination revealed vacuolated cytoplasm with areas of cytoplasmic clearing; the cells stained positively for cytokeratin AE1/AE3, CAM5.2, and PAX8. Cutaneous metastatic RCC was …
AE1/AE3 - Wikipedia
WebThe final diagnosis of an LELC was confirmed, after complete tumor resection, by the histological pattern and immunohistochemistry, which showed that the tumor was positive for cytokeratin (AE1 ... WebGeneral description. Anti-cytokeratin (OSCAR) is well-suited to distinguish epithelial carcinoma from non-epithelial malignancies and is used to aid epithelial tumor classification. This antibody has been used to characterize the source of various neoplasms and to study the distribution of keratin containing cells in epithelia during normal ... incivility example in nursing
Cytokeratin AE1/AE3, IHC with Interpretation - Quest …
WebCytokeratin pan is part of a subfamily of intermediate filament proteins that are characterized by remarkable biochemical diversity, and represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight between 40 kDa- 68 kDa, and an isoelectric pH between 4.9-7.8. WebAnti-cytokeratin, low molecular weight (AE1) labels most acidic keratins; therefore, it is a broadly reactive antibody staining most epithelia and their neoplasms. Members of the … WebThe stringent, but broad, specificity of pooled AE1/AE3 antibody has made this preparation very useful as a general stain for normal and neoplastic cells of epithelial origin. Anti-Keratin AE1 recognizes the 56.5, 50, 50’, 48, and 40 kD keratins of the acidic subfamily. incivility examples in nursing