Cinnamaldehyde cytotoxicity
WebIt is worth mentioning that according to Ibrahim et al., compounds 24, 28, 32, and 33 have shown variable cytotoxicity on A549 and H1299 cell lines . Again, these cytotoxic effects are worth further investigation. Compounds 6, 24, and 33 are derivatives of coniferyl aldehyde that contain cinnamaldehyde nuclei . WebNov 7, 2024 · In order to prevent the overdose-induced cytotoxicity, the MTT assay was first carried out to assess the reasonable treatment concentrations of the cinnamaldehyde-related compounds. As shown in Figure 1 b, at a concentration of 200 μM, cinnamaldehyde and 2-methoxy cinnamaldehyde caused a lower cellular survival (<95%).
Cinnamaldehyde cytotoxicity
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WebJan 1, 2004 · Cinnamaldehyde has also been observed to induce apoptosis in cancer cell lines [55] and may have contributed to apoptosis-inducing potential of CBD in our study. ... ... CBD did not induce any... WebApr 30, 2016 · Cinnamaldehyde and eugenol reduced the telomere lengths as compared to the untreated cells notably, but insignificantly when compared with DMSO treated hASCs. ... Thompson DC, Constantin-Teodosiu D, Moldéus P. Metabolism and cytotoxicity of eugenol in isolated rat hepatocytes. Chem Biol Interact. 1991; 77:137–147. [Google Scholar] 38.
WebOn comparing the cytotoxicity data of ACE at 1.28 mg/mL (containing 10.24 μM cinnamaldehyde) with that of commercial cinnamaldehyde at 10 μM concentration … WebHerein, an atomically-precise cinnamaldehyde derivatived metal-organic Cu(I) complex (denoted as DC-OD-Cu) was rationally constructed. DC-OD-Cu could preferentially accumulate in the mitochondria of HeLa cells due to the mitochondria-targeting ability of triphenylphosphine, which was accompanied by the generation of large amounts of highly ...
WebJul 16, 2024 · On the other hand, the genotoxicity of perillaldehyde and cinnamaldehyde are potential concerns due to the presence of α and β-unsaturated aldehydes in their structures; these unsaturated aldehydes are electrophilic and can react with electron-rich macromolecules, including DNA, to form DNA adducts [ 8 ]. WebOct 24, 2005 · testing with 1% and 2% cinnamaldehyde has been reported. It is interesting to note that in the same group of patients, 18.7% reacted to 2% cinnamaldehyde and …
WebOver the years, essential oils (EOs) and their compounds have gained growing interest due to their anti-inflammatory, antimicrobial, antioxidant, and immunomodulatory properties. The aim of this study was to evaluate the effect of eight commercially available EO-derived compounds ((R)-(+)-limonene, (S)-(−)-limonene, sabinene, carvacrol, thymol, …
WebOct 31, 2024 · Disk diffusion assay confirmed the antifungal activity of magnoflorine and revealed that this activity was stable over 3 days compared to those of berberine and cinnamaldehyde. Cytotoxicity testing showed that magnoflorine could potentially be used in a clinical setting because it didn’t have any toxicity to HaCaT cells even in … inclines on treadmillsinc church iconWebObjective: The purpose of this experiment was to explore the effect of Solid lipid nanoparticles (SLNs) on improving the oral absorption and bioavailability of cinnamaldehyde (CA). Methods: CA-SLNs were prepared by high-pressure homogenization and characterized by particle size, entrapment efficiency, and … inclining definition synonymsWebLung cancer is a malignant tumor characterized by a rapid proliferation rate, less survivability, high mortality, and metastatic potential. This review focuses on updated research about the clinical application of traditional Chinese medicine (TCM) as an adjuvant therapy to lung cancer treatment and the mechanisms of TCM effect on lung cancer in … inclining bed framesWebCytotoxicity and effects of curcumin and cinnamaldehyde hybrids on biofilms of oral pathogens . Authors Vanessa Rodrigues Dos Santos 1 , Karina Sampaio Caiaffa 1 , Warlley Campos de Oliveira 1 , Jesse Augusto Pereira 1 , Gabriel Flores Abuna 2 , Carlos Roberto Polaquini 3 , Luís Octávio Regasini 3 , Aimée Maria Guiotti 4 , Cristiane Duque 1 inclining bed frameWebJan 1, 2024 · Chitosan microparticles as entrapment system for trans- cinnamaldehyde: Synthesis, drug loading, and in vitro ... (pH = 6.5) which reveals a potential anti-cancer … inc church of christWebJun 1, 2024 · Metabolism plays a key role in chemical genotoxicity; however, most mammalian cells used for in vitro genotoxicity testing lack effective metabolizing enzymes. We recently developed a battery of TK6-derived cell lines that individually overexpress 1 of 8 cytochrome P450s (CYP1A1, 1A2, 1B1, 2A6, 2B6, … inclining bed base